Microchip-based chromatographic devices are more and more sought and attractive. Portable and disposable, they can analyse very small volumes such as nanoliters. However they require synthesis of innovative stationnary phases. The laboratory offers a new method to photograft polymers on surfaces of plastic microfluidic channels.

To keep robustness and performance of microfluidic chromatographic devices, stationnay phases must be anchored covalently and homogeneously to channels’ walls.

The laboratory has developped a new one-step method for the simultaneous in situ synthesis and anchoring of organic monolith inside COC (Cyclic Olefin Copolymer) microchip channel.

ADVANTAGES / NOVELTY

Simple, effective and economical process:

• Only one reactive medium
• Only one irradiation
• Only one type of polymer
• Only one nature of monolith: better separative performance.

Versatile process:

• On various thermoplastic substrates
• Various monomers.

APPLICATIONS

Microchip-based chromatography

RESEARCH TEAM
Karine Faure
Institut des Sciences Analytiques (ISA)        
UMR 5280, CNRS, UCBL

Your technology officer
Christian Chapelle
christian.chapelle@universite-lyon.fr
Tel. +33(0)4 37 37 20 09